Neuroplasticity and Chronic Pain: Retraining the Brain’s Pain Pathways
One of the most difficult health issues of our day is chronic pain. Over one in five people experience pain that interferes with their sleep, mood, mobility, and general quality of life and lasts longer than is typical.
In the past, it was believed that pain was a direct indication of injured tissue. However, recent discoveries in neuroscience have shown that pain is produced in the brain rather than being only a mirror of the body.
This change has significant ramifications for how people and practitioners see pain. The same mechanisms that sustain chronic pain can also be used to lessen it.
Neuroplasticity, the brain’s capacity to remodel its pathways, influences pain. PEMF, microcurrent, biofeedback, and biofield interventions are examples of energy and frequency-based therapies that are starting to show potential as instruments to assist with this retraining.
What is pain from a brain-based perspective?
Although pain is constantly there, tissue damage is not necessarily the cause of it. According to neuroscientists, pain is a brain output that is created by a complex interplay between environmental cues, emotional state, prior experiences, and sensory input.
One mechanism is central sensitization, which occurs when brain and spinal cord neurons become hyperresponsive, enhancing signals and producing a chronic pain state even in the absence of damage.
These alterations eventually result in maladaptive neuronal maps. Functional imaging studies, for instance, reveal that individuals with persistent back pain frequently have aberrant activity not just in sensory areas of the brain but also in areas related to memory and emotion.
This implies that, like learning to ride a bicycle, the brain can “learn pain.” And it can be unlearned with focused therapies that take advantage of neuroplasticity.

How does neuroplasticity help in pain retraining?
The brain’s capacity to create new connections and rearrange pathways in response to experience is known as neuroplasticity.
Chronic pain can continue because of this adaptability, but it also creates opportunities for recovery.
Retraining the brain involves:
- Lowering hypersensitivity in pain circuits by disabling hyperactive pain alarms.
- Establishing new connections (instructing the brain that touch, movement, or surroundings are safe instead of dangerous).
Conventional rehabilitation already has examples. By remapping sensory and motor cortices, mirror treatment helps patients with phantom limb pain see their intact limb moving in front of them.
Similar to this, graded motor imagery rewires brain-body connections by assisting patients in progressively seeing and then performing movement without causing pain.
Due to this basis, pain is a prime target for integrative methods that incorporate energetic and supportive physical therapies with brain retraining.

What energy therapies can help with neuroplastic pain care?
A growing body of research suggests that noninvasive, energy-based interventions can help modulate neuroplasticity and support pain relief.
PEMF (Pulsed Electromagnetic Field Therapy)
PEMF transmits mild electromagnetic pulses that affect neuronal signalling and cellular function. According to studies, PEMF may improve circulation, lessen inflammation, and alter brain excitability, all of which are factors in neuroplastic transformation.
For instance, daily PEMF sessions significantly reduced pain in patients with osteoarthritis in their knees when compared to a placebo.
Biofeedback and Bioresonance
Through biofeedback, people can learn to intentionally control physiological functions such as muscle tension and heart rate variability (HRV). Patients can learn to reduce stress reactions, which are a key factor in chronic pain loops, by receiving real-time feedback.
Biofeedback’s neuroplastic potential was highlighted by a meta-analysis that revealed it decreased the frequency and intensity of chronic migraines. Rebalancing the body’s electromagnetic impulses is the goal of bioresonance, which is little researched but could support nervous system retraining.
Microcurrent Therapy
Microcurrent therapy uses very low-level electrical currents to stimulate tissues at the cellular level. Evidence suggests it can increase mental function and promote nerve repair, creating conditions for neuroplastic healing.
Clinical applications include treating neuropathic pain, fibromyalgia, and post-surgical recovery.
Biofield Therapies
Rebalancing the subtle energy field surrounding the body is the goal of interventions like quantum healing and biofield tuning.
Early investigations indicate that these therapies can enhance emotional control and lower stress, two important elements in pain perception, though further research is required.
Practical Applications for Practitioners and Individuals
Chronic pain care is most effective when it is multi-modal, addressing body, brain, and energy together.
For practitioners (chiropractors, TCM doctors, functional nutritionists, holistic MDs):
- Combine frequency-based therapies with mindfulness or cognitive pain retraining approaches.
- Use PEMF or microcurrent to reduce pain signalling, then engage patients in movement or imagery therapy to reinforce positive neural pathways.
- Integrate biofeedback to help patients regulate stress and autonomic imbalances tied to pain.
For biohackers and individuals seeking self-care:
- Explore daily PEMF or microcurrent sessions to support neural repair.
- Practice HRV biofeedback using a wearable device to calm the nervous system.
- Use gentle graded movement and visualization to remap safe, pain-free movement.
- Support brain rewiring with sleep optimization, meditation, and anti-inflammatory nutrition.

Chronic pain is a reflection of how the brain has rewired itself through neuroplasticity, not merely a physical issue. The good news is that it is possible to retrain pain pathways.
Non-invasive methods to assist this process include energy- and frequency-based therapies like PEMF, biofeedback, microcurrent, and biofield interventions.
They enable both patients and practitioners to transition from pain into resilience when combined with movement, mindfulness, and lifestyle modifications.
Chronic pain is more than just “mental.” It is ingrained in the wiring of your brain, which can be altered with the correct resources.
Further Reading
Cognitive and emotional control of pain and its disruption in chronic pain – Explores how brain regions tied to emotion and cognition shape pain perception and how this system changes in chronic pain.
https://pubmed.ncbi.nlm.nih.gov/23719569/
Mindfulness-based treatment of addiction: current state of the field and envisioning the next wave of research – Shows how mindfulness practices leverage neuroplasticity to reduce both chronic pain and stress-related conditions.
https://pubmed.ncbi.nlm.nih.gov/29669599/
How neuroimaging studies have challenged us to rethink: is chronic pain a disease? – Early but foundational work showing brain changes in chronic pain and reframing pain as a disease of the nervous system.
https://pubmed.ncbi.nlm.nih.gov/19878862/
EEG Correlates of Self-Managed Neurofeedback Treatment of Central Neuropathic Pain in Chronic Spinal Cord Injury – Demonstrates how neurofeedback training can modify brain activity and reduce pain in patients.
https://pubmed.ncbi.nlm.nih.gov/31404253/
Disclaimer:
This information is for educational purposes only and does not constitute professional medical advice. Always consult a healthcare professional before incorporating any new therapy into your practice.
Do you want to see all the updates?
👉 Follow us on Instagram and Facebook and never miss a thing!